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Automated Solid Phase Extraction (SPE)
 
GERSTEL SPE

Performing Solid Phase Extraction (SPE) manually can be time consuming and nerve-racking, especially when recovery and reproducibility are lacking due to sample variability. If SPE can be reliably automated, it becomes a much more efficient and reproducible process. The GERSTEL Multi Purpose Sampler (MPS) with Automated SPE Option for standard cartridges provides several benefits compared with manual SPE:

  • Improved recovery, precision and reproducibility
  • Maximized sample throughput by performing SPE during GC or LC analysis of the preceding sample
  • More than 50 percent time saving for overall analysis, compared to manual process

Following the SPE clean-up steps, the MPS can introduce the sample extract directly to an LC/MS or GC/MS system for analysis. Alternatively, the MPS can be used as a stand-alone sample preparation robot, preparing samples for multiple LC/MS or GC/MS systems in your laboratory.

The GERSTEL SPE enables automated sample preparation and analysis even for complex samples. Samples are prepared in a simple and safe manner combining accurate results with high throughput.

   Easy transfer of your established manual methods
The GERSTEL SPE is based on standard 1 mL, 3 mL, and 6 mL SPE cartridges. Manual SPE methods can be directly transferred to the MPS and automated.

   High throughput
Analysis of up to 98 samples including sample preparation using standard SPE cartridges.

   Efficient
All sample preparation steps are performed during analysis of the preceding sample for highest productivity and system utilization.

   Optimal timing
All samples receive identical treatment for best reproducibility. Sample introduction to the GC/MS or LC/MS system follows immediately after sample preparation.

   Highly controlled analysis conditions
Defined volumes and constant flow rates provide highly reproducible conditions and optimal results.

   Internal Standard Addition
Automated liquid standard addition provide improved Quality Assurance.

   Contamination free
Transfer of eluent from the SPE cartridge to the sample vial is performed using a disposable syringe needle into a closed vial, eliminating the risk of carry over.

    Simple concept, highly rugged and efficient
Conditioning, extraction and elution of the cartridge is performed in one dedicated module with minimal movement of the cartridge ensuring highest efficiency and ruggedness.

   Integrated method for SPE and GC/MS or LC/MS analysis for simple 
   and error-free control of the complete system.
The MPS is a fully automated sample preparation and sample introduction robot for GC/MS and LC/MS. The complete system is easily and efficiently controlled from the Agilent ChemStation software or from the GERSTEL MAESTRO software. Sample preparation steps, including dilution, mixing, adding standards or derivatization are picked by mouse-click from a simple menu.
One method and one sequence table control the complete system including sample prep and GC/MS or LC/MS analysis.

Product Video:

SPE (low resolution 7 MB)

SPE (high resolution 15 MB)

Document:

SPE flyer (pdf)

Spec DHS

 

 

Applications:
AppNote 07/2006
Safe and Efficient Detection of Chloramphenicol in Food using Automated SPE